Cell Biology of HOst-Pathogen Interactions

In the Lamason lab, we investigate how intracellular bacterial pathogens hijack host cell processes to promote infection.

In particular, we study how Rickettsia parkeri and Listeria monocytogenes move through our tissues via a process called cell-to-cell spread. We utilize cellular, molecular, genetic, biochemical and biophysical approaches to elucidate the mechanisms of spread in order to reveal key aspects of pathogenesis and host cell biology.


August 26th, 2019: Welcome to the lab David! David Brinkley, a recent graduate of Amherst College, joins the team as our lab technician.

August 9th, 2019: Farewell to our first Lamason Lab MSRP student, Julissa Burgos. Thanks for an awesome summer and good luck in the future!

August 1st, 2019: Listeria are on the cover of MBoC! Read up on our RNAi screen for cell-to-cell spread regulators and see the MIT News Brief here.

July 25th, 2019: New funding for the Lamason lab!! We were just awarded a Surdna Junior Faculty Research Fund from MIT!

June 26th, 2019: The lab’s first manuscript was just accepted at MBoC! Thanks to Allen, Cassandra, and Arianna, as well as our collaborators Indro and Vida for their help getting us to this big milestone.

June 12th, 2019: Cassandra gave a fantastic talk about her work on the secreted effector Sca4 at this week’s Building 68 MIT Biology retreat.

June 3rd, 2019: Welcome to the lab Julissa! Julissa Burgos will be working in the Lamason lab this summer as part of the MIT Summer Research Program (MSRP-Bio).

May 28th, 2019: This week we welcomed our newest lab member, Yamilex Acevedo-Sánchez! Yami is a first-year graduate student in the Department of Biology who will be joining our quest to explore the mechanisms of pathogen spread. Welcome to the team, Yami!!

More news


RNAi screen reveals a role for PACSIN2 and caveolins during bacterial cell-to-cell spread .

RNAi screen reveals a role for PACSIN2 and caveolins during bacterial cell-to-cell spread.

Building 68 Retreat 2019