Cell Biology of HOst-Pathogen Interactions
In the Lamason lab, we investigate how intracellular bacterial pathogens hijack host cell processes to promote infection.
In particular, we study how Rickettsia parkeri and Listeria monocytogenes move through our tissues via a process called cell-to-cell spread. We utilize cellular, molecular, genetic, biochemical and biophysical approaches to elucidate the mechanisms of spread in order to reveal key aspects of pathogenesis and host cell biology.
RECENT Lab News
April 22nd, 2019: Emily was selected to be a Johnson & Johnson UROP scholar. This program will fund her full-time work in the lab this summer, as well as provide scholars with valuable networking and career guidance from MIT faculty. CONGRATULATIONS to Emily!
April 14th, 2019: Cassandra and Allen set-up a creative and fun way to describe the work we do in the lab for the MIT Microbial Fair today. Even the littlest Lamason got to join in on the fun and practice her cell-to-cell spread.
April 4th, 2019: The lab’s newest paper is live on bioRxiv. In this paper, we did a targeted RNAi screen focused on host intercellular communication regulators and came up with 22 genes that are important for Listeria cell-to-cell spread. This work reveals novel host factors that are hijacked by pathogens, and highlights how studying the process of spread could help us understand the regulatory mechanisms of host intercellular communication better.
March 12th, 2019: Biology graduate student Elizabeth Hemenway started her second rotation with us this week. Welcome to the lab!
February 19th, 2019: The Lamason Lab keeps growing. This week we welcomed MIT Undergraduate Desmond Edwards to the lab as our newest UROP. Welcome!
February 5th, 2019: Yamilex Acevedo-Sanchez from the Biology department just started in the lab for her first rotation. Welcome Yami :)
January 7th, 2019: New year, new rotons! This month we welcome Microbiology student Mandy Levine to the lab for her rotation.