Cell Biology of HOst-Pathogen Interactions
In the Lamason lab, we investigate how intracellular bacterial pathogens hijack host cell processes to promote infection.
In particular, we study how Listeria monocytogenes and Rickettsia parkeri move through our tissues via a process called cell-to-cell spread. We utilize cellular, molecular, genetic, biochemical and biophysical approaches to elucidate the mechanisms that promote spread to reveal key aspects of pathogenesis and host cell biology.
Bacterial Cell-to-cell spread